>B. Pharmacy Sem- Vth Examination December 2010(Pharmacology – II) ; GTU B. Pharmacy Sem- Vth Examination December 2010 question papers ; GTU Pharmaceutical Pharmacology – II question paper

>Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem- Vth Examination December 2010
Subject code: 250005
Subject Name: Pharmacology – II
Date: 18 /12 /2010 Time: 02.30 pm – 05.30 pm
Instructions: Total Marks: 80
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Write different stages of general anaesthesia. Write in brief about pre-anesthetic
medication.
06
(b) Write mechanism of action of benzodiazepines. 05
(c) Write note on Glutamate as a central neurotransmitter. 05
Q.2 (a) Classify antipsychotic drug. Write a note on atypical antipsychotic drugs. 06
(b) Write a note on Selective Serotonin Reuptake Inhibitors (SSRIs). 05
(c) Classify antiepileptic drugs according to mechanism of action. Write
pharmacokinetic and adverse effects of phenytoin.
05
Q.3 (a) Classify drugs used in Parkinsonism. Why Carbidopa is used in combination with
levodopa?
06
(b) Classify CNS stimulants and write a note on psychostimulants. 05
(c) Write a note on opioid agonists. 05
Q.4 (a) Classify Non-steroidal anti-inflammatory analgesics. Write a note on COX-2
inhibitors.
06
(b) Write note on Drug dependence. 05
(c) Write a note on Disulfiram 05
Q.5 (a) Classify antihypertensive agents. Write mechanism of action and therapeutic uses
of drug having adverse effect “dry cough”
06
(b) Drugs used in hypertensive emergencies and urgencies 05
(c) Write mechanism of action and pharmacological actions of cardiac glycosides 05
Q. 6 (a) Classify antiarrhythmic agents. Write mechanism of action and adverse effect of
Quinidine
06
(b) Write mechanism of action, adverse effect and therapeutic effect of nitrates. 05
(c) Write a note on fibrinolytic agents. 05
Q.7 (a) Classify diuretic agents. Write a note on thiazide diuretics 06
(b) Classify lipid lowering drugs. Write a note on HMG Co-A reductase inhibitors 05
(c) Write a note on :
1. Plasma expanders
2. Viral vectors used for gene therapy
05
*********

>B. Pharmacy Sem- Vth Examination December 2010(Pharmacognosy IV) ; GTU B. Pharmacy Sem- Vth Examination December 2010 question papers ; GTU Pharmaceutical Pharmacognosy IV question paper

>Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem- Vth Examination December 2010
Subject code: 250006
Subject Name: Pharmacognosy IV
Date: 20 /12 /2010 Time: 02.30 pm – 05.30 pm

——————————————————————
Instructions: Total Marks: 80
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1(a)Answer the following
Describe Photosynthesis
06
(b) Write brief note on Tracer-technique 05
(c) Give biosynthetic pathway for tyrosine 05
Q.2
(a)
Answer the following
Give pharmacognosy of Quinazoline alkaloid containing drug
06
(b) Define and classify Alkaloids 05
(c) Describe properties and general tests for identification of Alkaloids 05
Q.3(a)Answer the following
Discuss life cycle of Ergot
06
(b) Enlist alkaloids with reduced Pyridine derivative and give its
chemical constituents and uses05
(c) Write a brief note on Indian Ephedra 05
Q.4(a)Answer the following
Give pharmacognosy of Coffee and describe procedure for isolation
of caffeine
06
(b) Give the specific chemical tests for followings;
i) Quinine ii) Atropine iii) Caffeine iv) Ergotoxine v) Strychnine
05
(c) Draw chemical structure of followings;
i) Cocaine ii) Morphine iii) Pilocarpine iv) Quinine v) Reserpine
05
Q.5(a)Answer the following
Enlist Tropane Alkaloids and write Pharmacognostic profile of any
one drug contain it.  06
(b) Give pharmacognostic details of an anti-cancer drug 05
(c) Describe pharmacognosy of drug having anti-malarial activity 05
Q. 6(a)Answer the following
Give adulterant and substitutes of Pilocarpus and Cola
06(b) Describe microscopical characters of Vasaka leaf. 05
(c) Write macroscopical characters of Datura leaf and Kurchi bark 05
Q.7(a)Answer the following
Describe pharmacognosy of Vachhnag.  06
(b) Define and write types of stereoisomerism giving suitable examples 05
(c) Write an assay on stereoisomerism of Alkaloids 05
***************

>B. Pharmacy Sem- Vth Examination December 2010(Hospital Pharmacy, Community Pharmacy and Forensic Pharmacy) ; GTU B. Pharmacy Sem- Vth Examination December 2010 question papers ; GTU Hospital Pharmacy, Community Pharmacy and Forensic Pharmacy question paper

>Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem- Vth Examination December 2010
Subject code: 250001
Subject Name: Hospital Pharmacy, Community Pharmacy and Forensic Pharmacy
Date: 11 /12 /2010 Time: 02.30 pm – 05.30 pm
Instructions: Total Marks: 80

1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define ‘Hospitals’ and classify them into various types depending upon
different criteria.
06
(b) Explain the term ‘Hospital Formulary’. Mention the objectives/ advantages and
disadvantages of the same.
05
(c) Write a note on ‘Drugs Inspectors’ under Drugs and Cosmetics Act. 05
Q.2 (a) Define the term ‘Hospital Pharmacy’ and discuss various functions of the same. 06
(b) Write a note on Medical Termination of Pregnancy Act. 05
(c) Discuss various sources of Information on drugs. 05
Q.3 (a) Define the term ‘Pharmacy and Therapeutic Committee’. Discuss the
objectives/ major roles and composition of the same.
06
(b) Discuss the conditions to be satisfied for obtaining the license for manufacture
of drugs other than those specified in Schedule C and C1 and Schedule X.
05
(c) Write a note on ‘Patient Medication Profile’. 05
Q.4 (a) Enlist the goals of Budget. Enumerate the main divisions of Budget and discuss
in detail one of the divisions dealing with Capital investments.
06
(b) Mention general labeling requirements that should appear on the label of
containers of all the drugs under Drugs and Cosmetics Act. Also write special
labeling requirements/ precautions that should appear on the labels of
ophthalmic solutions/suspensions.
05
(c) Discuss the records and reports in context to cases on Drug Interactions and
Adverse reactions.
05
Q.5 (a) State the object of Drug (Price Control) Order1995 and define ‘Bulk drugs’ and
‘Formulations’ under the same. Explain the formula used for calculation of
retail price of drug formulations.
06
(b) Write a note on preparation of ‘Hospital Formulary’. 05
(c) Discuss in detail Medication Error. 05
Q. 6 (a) Discuss various steps involved in purchase procedure with reference to
Pharmacy Management Service.
06
(b) Write a note on Patient Treatment Records and Auxiliary Reporting. 05
(c) Write a note on Medical Tourism and Development. 05
Q.7 (a) (i) Enumerate various administrative agencies (under three distinct headings)
provided for efficient administration of Drugs and Cosmetics Act.
06
(ii) Which information is provided by Schedule B, Schedule C and C1 and
Schedule H.
(b) State the objectives of Inventory Control. Enumerate various methods of
Inventory Control and write a note on ABC Analysis.
05
(c) State the object of Drugs and Magic Remedies Act. Mention the classes of
Advertisements exempted under the said Act.
05
***************

>B. Pharmacy Sem- Vth Examination December 2010(Pharmaceutical Chemistry – V(Bio-Chemistry) ; GTU B. Pharmacy Sem- Vth Examination December 2010 question papers ; GTU Pharmaceutical Chemistry – V(Bio-Chemistry) question paper

>Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem- Vth Examination December 2010
Subject code: 250003
Subject Name: Pharmaceutical Chemistry – V(Bio-Chemistry)
Date: 15 /12 /2010 Time: 02.30 pm – 05.30 pm
Instructions: Total Marks: 80
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Describe the secondary structure of protein. 06
(b) Discuss the mechanism of enzyme inhibition. 05
(c) Discuss the transport mechanism across cell membrane. 05
Q.2 (a) What is glycolysis? Give their metabolic reaction with energetics. 06
(b) Give the structure and function of phospholipids. 05
(c) Describe the reaction of galactose metabolism. 05
Q.3 (a) Write about the mechanism of enzyme action. 06
(b) Write about the component and reaction of respiratory chain. 05
(c) Discuss the edman’s techniques for determination of sequence of amino acids. 05
Q.4 (a) Define the vitamins. Write about the structure and coenzme activity of
riboflavin.
06
(b) Write about the significance of enzymes in diagnosis of disease. 05
(c) Define and classify carbohydrates with suitable examples. 05
Q.5 (a) Write shot note on followings.
1. Essential fatty acid. 2. Lipoproteins
06
(b) Discuss the importance of hormone in regulation of blood sugar level. 05
(c) Write the synthesis of ATP and give their biological significance. 05
Q. 6 (a) Write about the reaction and energetics of citric acid cycle. 06
(b) Define the proteins. Classify them with suitable examples. 05
(c) Explain the glycogenolysis with metabolic reaction. 05
Q.7
(a)
Differentiate between (i) epimers and anomers
(ii) saturated fatty acid and unsaturated fatty acid
06
(b) Write about the significance of folic acid and patothenic acid as co enzyme. 05
(c) Write about the metabolic reaction of pentose phosphate pathway. 05
***************

>B. Pharmacy Sem- Vth Examination December 2010(Pharmaceutical chemistry-VI (Medicinal)) ; GTU B. Pharmacy Sem- Vth Examination December 2010 question papers ; GTU Pharmaceutical chemistry-VI (Medicinal) question paper

>Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem- Vth Examination December 2010
Subject code: 250004
Subject Name: Pharmaceutical chemistry-VI (Medicinal)
Date: 13 /12 /2010 Time: 02.30 pm – 05.30 pm
Instructions: Total Marks: 80

1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Enlist various physicochemical parameters. What is importance of geometrical
and optical isomers for biological action of drug?
06
(b) What is isosterism and bioisosterism? Classify them and give their recent
application.
05
(c) Write a note on (i) Protein binding of drug
(ii) Partition coefficient
05
Q.2 (a) What are heterocyclic compounds? Give the preparations and properties of Furan. 06
(b) Explain the following statements (Any three)
(i) Pyridine is stronger base than aniline
(ii) Furan is less aromatic than Thiophene
(iii) Electrophilic substitution takes place at 2-position in Pyrrole
(iv) Pyrrole cannot be titrated using conc. nitric acid
05
(c) Give the synthesis and reactions of pyrimidine and isoquinoline 05
Q.3 (a) Classify the drug acting on respiratory tract with chemical structure from each
class
06
(b) Write a note on (i) Antiasthmetics (ii) Mucolytic agents 05
(c) Write a note on radio contrast media 05
Q.4 (a) What are gastrointestinal agents. Classify them with examples. 06
(b) Write a note on (i) Proton pump inhibitors (ii) Prokinetic agents 05
(c) Give synthesis of Ranitidine and Diphenoxylate 05
Q.5 (a) What are autocoids? Enlist various histaminic receptors. Classify H1-antagonist
with examples.
06
(b) Discuss SAR of antihistamines 05
(c) Give the synthesis of Chlorpheniramine and Citrizine. 05
Q. 6 (a) Give following synthesis with reaction mechanism (Any two)
(i) Skraup synthesis
(ii) Hantzsch pyridine synthesis
(iii) Fischer-Indole synthesis
06
(b) What is difference between antacids & antisecretary agents? Write a note on
antisecretary agents.
05
(c) What are eicossanoids? Give examples of various eicossanoids. Write a note on
prostaglandines.
05
Q.7 (a) Write a note on Ferguson’s principle 06
(b) Give any two synthesis and any two reactions of Imidazole & Thiazole. 05
(c) Write a note on expectorants & antitussive agents 05
***************

>B. Pharmacy Sem- Vth Examination December 2010(Pharmaceutical Microbiology- I) ; GTU B. Pharmacy Sem- Vth Examination December 2010 question papers ; GTU Pharmaceutical Microbiology- Iquestion paper

>Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem- Vth Examination December 2010
Subject code: 250002
Subject Name: Pharmaceutical Microbiology- I

———————————————————————–
Date: 16 /12 /2010 Time: 02.30 pm – 05.30 pm
Instructions: Total Marks: 80
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Define pharmaceutical microbiology. Describe its scope in brief. 06
(b) Describe contribution of ‘Louis Pasteur’ in microbiology. 05
(c) Write note on bacterial flagella. 05
Q.2 (a) Explain: Motility, Pathogenicity, Virulence 06
(b) Describe type of bacteria on the basis of : 05
i) Nutritional requirement ii) Temperature requirement
(c) Classify staining techniques. Discuss gram staining. 05
Q.3 (a) Enlist methods for isolation of bacteria. Discuss streak plate method. 06
(b) Write note on Scanning Electron Microscopy 05
(c) Describe factors affecting disinfection process in brief 05
Q.4 (a) Enumerate methods for evaluation of disinfectants. Describe Rideal-Walker test. 06
(b) Explain: Thermal death point, Thermal death time, Iodophore, Bioburden,
Bactericide. 05
(c) Define ‘sterilization’. Classify different methods for the same with mechanism of
action. 05
Q.5 (a) What is cold sterilization? Write note on fractional sterilization. 06
(b) Explain: D- value, F- value, Z- value, Q10- value, Inactivation factor 05
(c) Describe biological indicators for monitoring sterilization processes 05
Q. 6 (a) Enlist methods for sterility testing. Discuss direct inoculation method. 06
(b) Explain: Sterility, SAL, Incineration, MIC, Zone of inhibition 05
(c) Describe cup-plate method for microbiological assay 05
Q.7 (a) Explain microbiological assay. Name microbes used in assay of: Amphotericin B,
Erythromycin, Carbenicillin, Rifampicin, Tetracycline. 06
(b) Discuss microbiological assay of cyanocobalamin 05
(c) Explain: Total count & Viable count. Describe photometric method for determining
total count. 05
***************

Follow

Get every new post delivered to your Inbox.